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Swelling between the thumb and index finger

In the past couple of hours my wife's right hand has begun to painfully swell between the web portion between the thumb and index finger. It has a knot/ lump, and it is painful to open and squeeze her hand closed. What is this?

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The swelling in your wife’s hand could be as a result of inflammation or build up of the tissue in the joints of the hand. This is usually referred to as edema and can be caused as a result of trauma or infections. Please consult a doctor as soon as possible. To find out more, log on to

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