Once alcohol reaches the bloodstream it generally metabolized at a rate of .015 of blood alcohol concentration (BAC) every hour. But,because BAC is a measure of proportion,it will take more drinks to make a larger individual reach a given blood alcohol concentration,and the amount of alcohol that is metabolized to maintain a rate of .015 per hour will also be larger. About 10 percent of alcohol leaves the body through the breath, perspiration,and urine. Almost all of the rest is metabolized by the liver. The usual fuel for liver cells is fatty acids,but in the presence of alcohol the liver will modify its diet to prevent a harmful buildup of alcohol that would damage other cells and organs. There is some evidence that normal alcohol intake makes the process more efficient to a point,creating a tolerance,though,in the long run,the metabolizing of alcohol permanently alters liver cells and decreases their ability to carry out normal functions as well as metabolizing alcohol. The accumulation of unused fatty acids can lead to cirrhosis,or fatty liver,and even liver failure.