Wow! I'm a Registered Nurse and the answer is NO!! Find someone to drive for you if you're taking the med. Your doctor doesn't care about your well being if he/she said that it's safe to drive while on Hydrocone(Vicodin or Lortab) or any other narcotics. They might as well have told you it's ok to get sloshed at the bar and hop in your car and drive. It's just as bad (and illegal). Of course people are going to do what they want to do whenever they want to, but if you have or cause an accident you'll see just how quick your doctor will come to your rescue/defense....THEY WON'T. If you gotta take the pain med, don't drive for AT LEAST 4 hours. I recommend doing what you gotta do first, get to your final destination and THEN take the pain med when you don't have to go anywhere. Most drunk drivers think they are driving just fine until they wreck or kill an innocent person. That "I felt fine" excuse or "I knew how the drug effected my judgment" crap doesn't stand up well when you're in court trying to explain a vehicular homicide you caused. Its the SAME THING with narcotics.
Hydrocodone does make you tired and I believe it states on the prescription bottle not to drive or operate heavy equipment. Even if your MD said it was ok, if something bad happens, you will be held liable and probably go to jail for having narcotics in your system while driving.
If you are in pain, which I guess is the reason for the meds, since the pills take at least 30 mins or longer to work, you can get a lot of errands done in that amount of time. If you're planning on being in the car longer, perhaps if they are pills & not capsules you can start off with 1/2 a pill and take the other half after you get back home or to your destination!
As long as you are alert on the medication and the doctor said it was ok then it should be fine. I take it and it doesn't make me sleepy at all. Actually it wakes me up. My doctor has told me that as long as this is the case then it is fine to drive on it.