If I liked the clothes, sure! I mean say I had some great clothes, I died and my daughters really liked a lot if my clothes. Id certainly hope they'd use them. Even if it wasn't a relative! If a friend really liked some of that stuff, I'd be thrilled that they were being used.
When grandma died she left us a house and a piano that her grandmother had given her. We kept and used both. We are currently going through the house three years later, and many family members and friends of the family have taken articles including clothes. We know she would be thrilled they are being used. I myself dont look to good in grandmas clothes though, but I have set aside a few keepsakes.