Humans. Okay, yeah, maybe I'm being a bit psychotic-sounding saying this, but humans have gone too long doing animal-testing. Why not let one selfish person try it out once and see if they want animals to do the same?
If its a life saving measure that cannot be tested in dummy models, then yes test, if its cologne, shampoo, etc, use the dummy models... Thanks to animal research, many diseases that once killed millions of people every year are either treatable or have been eradicated altogether. Immunizations against polio, diphtheria, mumps, rubella and hepatitis save countless lives, and the survival rates from many major diseases are at an all-time high, thanks to the discovery of new drugs, medical devices and surgical procedures. According to the American Cancer Society, the fight against cancer has seen 24 significant biomedical advances in the past 30 years.
None of them could have occurred without animal research.
Eight of the discoveries required the use of living animals, and virtually all of those that did not use animals relied on information gained from earlier animal studies. Six of the discoveries were recognized with a Nobel Prize, among them: the bone-marrow transplantation technique; cloning of the first gene; and discovery of proto-oncogenes in normal DNA, showing that a normal cell could have latent cancer genes.