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I took one amoxicillin 500 mg pill at 4:00am this morning it's now 9:00am can I take an advil cold & sinus 200mg what will happen

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Nothing will happen to you if you take Amoxicillin and Advil. There won't be any effect because Amoxicillin is an antibiotic whereas Advil is Motrin with Sudafed. You may inquire from your doctor for more particulars.

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do you have a sinus infection?

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Just a bad cold
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When having a bad cold you do not take any type of antibiotics even Amoxcillin.
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perfectly acceptable unless you are allergic to any of these meds. they do not interact with each other.

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