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Would you expect two children with the same two parents to have the same sets of chromosomes?

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No. Everyone has their very own set of chromosomes . If they were the exact same, everything else about them would be exactly the same.

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If two siblings share the same parents, they should share 50 per cent of their mother's chromosomes, and 50 per cent of their father's chromosomes. Additionally, each organism including human beings, has a unique number of chromosomes.

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All human beings have exactly the same number of chromosomes-48.
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I mean 46.
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Everyone has 46 chromosomes. 23 of these come from their mom, 23 from their dad. However, a pair of siblings are very unlikely to get the same chromosomes, since they'll probably get a different set from their mother then their sibling did. Look at it like this: Your mother has three chromosomes, a blue one, a red one, and a green one. You get a blue one, and a green one. Your sibling gets the green one, and the red one. You share 1 chromosome, but each have a different one besides that. Thus you look different. Makes sense?

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