In just about any way you can think of! England is an island, Antarctica is a continent, it is covered in snow and ice all the time, while England is much warmer and is much more suitable for farming and habitation. Antarctica has different wildlife such as penguins and seals . There are no permanent inhabitants and the average temperature year round is -58degrees Fahrenheit! If you require more detail try Google!
Antarctica - covered in ice year-round, 2.5 million square miles big, no 'ruler' it is shared, not populated year-round, only crossed and reach the 'center' in the last century, in a different place than England - different neighbors, no permanent settlements, no natural resources except ... ice. England - once a world power, a lot more people (I don't know how many - lots more the the south pole), part of a 'country' with Scotland, Wales and Ireland, has a 'working (with themselves and the world) population, has relatively close neighbors in France Spain and Holland, had trees as a resource, but used them all, uses peat for heat, an Aristocracy in the Royal family, in a more livable area than the poles and populated since before Roman times. There's a lot more differences, check out the encyclopedia or wikipedia.