The amount of time opana stays in your system is dependent on several factors. It depends on how much of the drug you have been taking and for how long. It also depends on how much fluid you drink and what type of diet you eat. Physical characteristics, such as body mass, weight, and height also play a part in the removal process.
Opana can be detected in a urine test up to four days after it has been taken. However, if you have taken this medication for prescription, make sure to bring the prescription with you to the urine test and all will be okay.