Yes, It can make you tired. Oxygen that your body utilizes to sustain normal function is carried by hemoglobin in your blood cells, which reaches your capillaries by way of your arteries. If your blood is thin, then there is less time for your body to make the exchange between delivering oxygen and extracting the waste products such as carbon dioxide to and from your body. Less oxygen equals fatigue.
I agree with Jocab; check with your doctor. Possible thin blood or anemia