A good way to get paint off of clothing is to use Murphy's oil soap. What you need to do is wet the spot with the paint on it then apply the murphy's oil soap and let it sit a few minutes. Then you take an old toothbrush you don't use anymore and scrub the spot and that should remove the paint.
This question does nor contain enough info..i.e. is the paint water base or oil base? That will determine the procedures to use..secondly, how long has the paint been on the clothes?..makes a difference