Bone marrow edema occurs as a result of fluid build up in bone marrow, according to Robert J. Daley, M.D. This fluid accumulation is normally caused by an injury, osteoporosis or tumors. Injuries that cause BME may include bone fractures, ligament injuries and bone bruises.Know More
The most common cause of BME is when a significant injury hits the bone, as fluid build up is the body's normal response to a break. A stress fracture due to osteoarthritis or osteoporosis also leads to fluid accumulation, notes Dr. Howard J. Luks. Bone death, also known as osteonecrosis, occurs when a blood vessel somehow does not supply blood to a bone. This injury, in turn, may cause BME.
Synovitis, or an inflammation of the synovial membrane lining the joints, may also cause BME. Symptoms of this disorder may not be present in some patients, although the most obvious sign is pain in the bone. The severity of pain depends on the type of underlying cause, notes Daley.
The easiest way for doctors to detect BME is an magnetic resonance imaging, or MRI, scan of the affected bone. BME causes bones to appear white in an MRI, according to the American Academy of Orthopaedic Surgeons. Bone marrow is a spongy substance inside long bones that produces blood cells for the body.Learn more about Conditions & Diseases
Bone marrow function tests help assess the health of a patient's bone marrow and determine if it is manufacturing normal amounts of each blood cell, explains the National Heart, Lung, and Blood Institute. Bone marrow contains stem cells that develop into platelets, white blood cells or red blood cells.Full Answer >
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According to the Atlas of Bone Marrow Pathology, bone marrow cellularity refers to the volume ratio of haematopoietic cells (cells that make blood cells) and fat. In newborns, bone marrow cellularity is normally 100 percent, but it decreases with age. Normal bone marrow cellularity in an adult is between 30 and 70 percent. Thus, hypercellular marrow is that which contains more than 70 percent haematopoietic cells.Full Answer >
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