The exact cause of bile duct cancer is unknown, according to Healthline, but scientists implicate mutations in the bile duct cells' DNA. Bile duct cancer is a type of liver cancer that starts in the bile duct cells. The bile duct is a tube that extends from the liver to the small intestines.Know More
There are three types of bile duct cancer, as outlined by Healthine.com. Each is classified by the location in which the cancer appears. The first group, called perinilar bile duct cancer, is the most common and occurs where the bile ducts merge and exit the liver. The second group is distal bile duct cancer, which occurs in the last part of the duct system that passes through the pancreas and ends in the duodenum. The third type is intrahepatic bile duct cancer, which occurs within the liver itself. The intrahepatic type comprises one in 10 cases of bile duct cancer.
Regardless of the type, bile duct cancer obstructs the flow of bile from the liver into the small intestines. Therefore, Healthline.com includes jaundice, which is a yellowing of the eyes, as the main symptom of bile duct cancer. Additional symptoms include weight loss, fatigue and weakness, decreased appetite, abdominal pain, itching and clay-colored stools.Learn more about Cancer
A rare disease, ampullary cancer forms in the ampulla of Vater, the area where the bile duct and pancreatic duct meet and empty into the small intestine, according to Mayo Clinic. Because ampullary cancer develops near the pancreas, liver and small intestine, it can be mistaken for periampullary cancers.Full Answer >
Although it is unclear what causes kidney cancer, or renal cell carcinoma, factors such as high blood pressure, inherited and acquired gene mutations, smoking, and obesity can increase an individual's risk for developing kidney cancer, states Mayo Clinic. How these factors lead to cancerous kidney cells is not known.Full Answer >
It is not clear what exactly causes the mutations in the throat that lead to throat cancer, according to Mayo Clinic. Factors such as tobacco use, the human papillomavirus, excessive alcohol use and a diet lacking in fruits and vegetables can increase the risk of developing throat cancer.Full Answer >
Some types of colorectal cancer are hereditary and caused by genetic abnormalities or mutations. Familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer are the most common types of inherited colorectal cancers, according to WebMD.Full Answer >