Better Medicine states that high platelet production is categorized as either primary thrombocythemia, which occurs for reasons unknown, or secondary thrombocytosis, which is caused by another condition, such as infection, anemia or cancer. A high platelet level means that the blood has an abnormal number of platelets.Know More
Platelets are tiny blood cell fragments made in bone marrow that help in blood clotting, according to Better Medicine. A healthy person normally has 150,000 to 450,000 platelets in every microliter of blood. Primary thrombocythemia is a condition wherein the bone marrow produces excessive platelets. In this case, high platelet levels occur as an independent condition without any other cause. Primary thrombocythemia can be inherited. In secondary thrombocytosis, high platelet production results from another condition. There are many diseases and conditions that lead to high platelets, including anemia, blood loss, chemotherapy, cancer, infection and inflammatory disorders.
Better Medicine notes that high platelet levels that occur due to serious diseases can result in severe complications and permanent damage, including bleeding, blood clots and brain damage. When caused by an underlying disease, high platelet levels are accompanied by other symptoms, such as weakness and bleeding. However, some people do not experience any symptoms, and high platelet levels are detected only by routine blood tests.Learn more about Conditions & Diseases
In reactive thrombocytosis, the platelet count is elevated due to another disorder, such as an infection, bleeding, iron deficiency, cancer, destruction of red blood cells, removal of the spleen, inflammatory disease or other blood condition, the Merck Manual states. If the primary problem is treated successfully, the platelet count returns to normal.Full Answer >
A high MPV, or a high number of large platelets, in an individual with a low platelet count indicates the release of platelets from the bone marrow into the blood circulation, according to Lab Tests Online. Unexplained bruising is a typical symptom of platelet deficiency.Full Answer >
Low platelet count, or thrombocytopenia, is caused by such conditions as an enlarged spleen, which may trap too many platelets and remove them from blood circulation; bone marrow destruction due to cancer and its treatment; and exposure to toxic chemicals, according to Mayo Clinic. Some anemias also reduce platelet count.Full Answer >
Pancytopenia causes low red blood cell count, anemia and low platelets with a fever in dogs. Pancytopenia does not refer to one specific disease, but rather to a number of different blood related deficiencies that cause these problems.Full Answer >