In some cases, inherited genetic mutations cause temporal wasting, also known as frontotemporal lobar degeneration, but in most cases, the cause is unknown. Further research must be conducted to discover the true cause, according to the National Institute on Aging.Know More
Scientists from the National Institute on Aging describe patterns of change in the brain seen in an autopsy after death, including loss of neurons and abnormal amounts or forms of proteins called tau and TDP-43. These proteins occur naturally in the body and help cells function properly. When the proteins do not work properly, for reasons not yet fully understood, damage occurs to neurons in specific brain regions.
Frontotemporal lobar disorders are grouped into three types that are defined by early symptoms. Behavioral variant frontotemporal dementia causes changes in personality, behavior, emotions and judgment. Primary progressive aphasia is characterized by changes in language ability, including speaking, understanding, reading and writing. Corticobasal syndrome, also known as supranuclear palsy or amyotrophic lateral sclerosis, is characterized by various difficulties with physical movement, including the use of one or more limbs, difficulty walking, frequent falls and poor coordination. Symptoms vary from one person to another and some symptoms are common to more than one disorder, making it difficult to identify which type of frontotemporal lobar disorder is present in the early stages of the disease.Learn more in Conditions & Diseases
The exact cause of psoriasis is not fully known, but scientists believe an immune system problem combined with a genetic predisposition and environmental factors causes the skin condition. Mayo Clinic indicates that overactive T cells in the immune system attack healthy skin as if they were attempting to heal a wound or fight infection. New skin cells rise to the surface before older skin cells slough off, creating patchy skin.Full Answer >
Also known as paresthesia, numbness in the toes has many different potential causes, according to MedicineNet.com. Usually, the numbness is caused by shoes that constrict the foot and compress the nerves. However, injury, nerve damage or irritation, and poor circulation are also common causes of paresthesia.Full Answer >
The exact causes of rheumatoid arthritis are not entirely known, but scientists believe that a combination of environmental and genetic factors may make people more susceptible to developing this condition. Â For example, researchers believe that either a viral or bacterial infection can trigger this disease if a person is genetically predisposed to it.Full Answer >
The cause of restless leg syndrome is not completely known, but many doctors believe it can be related to genetic factors, low iron levels in the brain or the result of various diseases. Restless leg syndrome, abbreviated as RLS, has also been shown to be a symptom of various diseases, including: peripheral neuropathy, chronic kidney failure or even diabetes.Full Answer >