Platelets should be transfused at a rate of 10 milliliters per minute for approximately 30 minutes, explains the Department of Pathology at the University of Michigan Health System. Platelets are typically transfused in cases of severe bleeding in people with a low platelet count and should be transfused quickly to receive their full benefit.Know More
It is always important to reassess bleeding and take a platelet count after a transfusion. The normal platelet count is between 150,000 and 400,000 per cubic millimeter. The American Cancer Society explains that the risk of dangerous bleeding becomes elevated when the count drops below 20,000 per cubic millimeter.
Platelets originate in the bone marrow from cells called megakaryocytes. They are fragmented cells in the blood that become activated when bleeding occurs. A decrease in platelets can occur because of decreased production in the bone marrow, increased destruction in the bloodstream or an increased destruction by the liver or spleen, according to MedlinePlus.
Platelet counts can also be increased in a condition called thrombocytosis, notes MedlinePlus. This can be directly due to primary thrombocytosis or may occur secondary to anemia, infection, cancer, medication side effects, polycythemia vera or splenectomy. People with elevated platelet counts have an increased risk of forming blood clots, which leads to serious medical problems.Learn more about Medical Ranges & Levels
The technical term for a low blood platelet count is thrombocytopenia, and treatments range from addressing the underlying condition, and, if applicable, blood transfusions or treatment for the disease idiopathic thrombocytopenic purpura (ITP). Some moderate cases, though, resolve on their own, according to Mayo Clinic.Full Answer >
A person can have low blood platelet count, or thrombocytopenia, because of genetic history or medical conditions, according to Mayo Clinic. Drugs such as those used in chemotherapy can also cause a low platelet count.Full Answer >
Low platelet count can be caused by acquired or inherited conditions, which may cause the body's bone marrow to decrease platelet production, according to the National Heart, Lung, and Blood Institute. The body may destroy or use up the platelets, or the spleen holds on to too many platelets.Full Answer >
Trapping of platelets in the spleen, reduced production of platelets, and increased platelet breakdown can all lead to low platelet count, according to Mayo Clinic. The blood normally has between 150,000 and 450,000 platelets per microliter. Each platelet lives about 10 days, so the body is continually replacing them.Full Answer >