In people that are not tolerant of opioids, a single dose of 40 milligrams or a total daily dose of 80 milligrams of oxycodone has the potential to cause fatal respiratory depression, according to DailyMed. While oxycodone is manufactured in 80 milligram controlled-release tablets, these larger doses are intended only for use in people who are opioid tolerant, as they too can cause fatal respiratory depression.Know More
Additionally, oxycodone controlled-release tablets are intended to be swallowed whole and not crushed or chewed, according to DailyMed. Doing so can also cause an overdose on oxycodone even in those people who would otherwise be tolerant of the larger dose.
Oxycodone is a powerful analgesic pain reliever that is prescribed for people who require relief from moderate to severe pain, according to DailyMed. Oxycodone is addictive and should never be used unless prescribed by a medical doctor to treat a current condition. Common side effects to taking oxycodone include a feeling of relaxation, euphoria, constipation, vomiting, dizziness, sweating, confusion and respiratory depression.
Oxycodone is a controlled substance and is often a target for theft, according to DailyMed. For this reason and for the safety of others, always dispose of unused oxycodone in a safe manner to prevent abuse.Learn More
The lethal dosage of zolpidem tartrate depends on several factors, including the individual's tolerance, gender and weight. Doses greater than 150 milligrams per kilogram of body weight are usually fatal. A dose of 10,200 milligrams is likely a lethal dose for an adult weighing 150 pounds.Full Answer >
The ingredients in Tylenol PM, acetaminophen and diphenhydramine, have different lethal doses. The lethal dose of acetaminophen in rats is 2,400 milligrams per kilogram, reports the Food and Drug Administration. The lethal dose of diphenhydramine is between 50 to 500 milligrams per kilogram, according to the National Institutes of Health.Full Answer >
The lethal dose of diphenhydramine, the generic name of Benadryl, varies significantly from person to person because of differences in weight and metabolism. There have been cases of people experiencing overdose symptoms with 500 milligrams of diphenhydramine and some cases where overdose is as high as 2,800 milligrams.Full Answer >
A lethal dose of Ambien in rats is 600 milligrams per kilogram, according to Safety Medical, which implies that to cause death, the drug would have to be ingested in large quantities. However, Ambien can affect the heart and breathing, causing fatal complications at much lower doses.Full Answer >