Marfan syndrome is inherited in an autosomal dominant pattern. It involves the mutation of the FBN1 or fibrillin-1 gene, a so-called dominant gene, and so only one copy of the mutated gene will produce the syndrome in offspring.Know More
Marfan syndrome affects the connective tissue of the body, rendering them weaker and more flexible than typical. It can result in a number of health problems including impaired vision as the lenses become dislocated or weak heart valves, causing irregular heartbeat, shortness of breath and more.
An individual carrying this dominant gene has a 50 percent chance of passing it along to their offspring. It is estimated that approximately 25 percent of Marfan syndrome cases are caused by a new, spontaneous mutation and not by inheritance of the faulty gene.Learn more about Conditions & Diseases
According to Mayo Clinic, serotonin syndrome occurs when a patient takes medications that cause high levels of the chemical serotonin to accumulate in the body. Serotonin syndrome likely occurs if a new medication is prescribed or can be attributed to the use of illegal drugs and dietary supplements.Full Answer >
According to Mayo Clinic, Down syndrome occurs in three variations and is caused by additional genetic material from chromosome 21. Cell division errors cause the chromosome abnormalities. The majority of Down syndrome cases, approximately 95 percent, are trisomy 21, which results from three copies of chromosome 21 instead of two copies.Full Answer >
Failed back surgery syndrome is a term that is used to describe the condition resulting when a person has an unsuccessful back or spine surgery. Failed back surgery syndrome is not an official diagnosis; it is a term used in the medical field.Full Answer >
Angelman syndrome is a genetic disorder that causes severe neurological and developmental disability, sleep disturbance, outbursts of laughter, seizures, and difficulty with balance and walking, according to Mayo Clinic. In spite of the debilitating nature of the condition, many people afflicted with Angelman syndrome experience normal life spans and happy personality traits.Full Answer >