A necrotic tumor is a tumor that has one or more areas of dead tissue, usually related to growth beyond the tumor's blood supply, says the Free Dictionary. Some researchers believe portions of tumors turn necrotic when they're deprived of oxygen, notes Japanese Journal of Clinical Oncology.Know More
Necrosis refers to the death of cells, and until recently, it was thought to be an unregulated occurrence during which the cell membrane is destroyed, says National Center for Biotechnology Information. New data shows that it may actually be a well-regulated process activated by particular stimuli. Unlike another type of cell death called apoptosis, necrosis usually causes inflammation that may be involved in tumor regression in patients undergoing anticancer therapy. However, when a tumor is developing, excessive necrosis results in more aggressive tumors because the inflammation caused by necrosis can stimulate their growth.
Carcinoma patients with some types of tumor necrosis are more likely to experience less favorable outcomes, including recurrence of disease, explains Japanese Journal of Clinical Oncology. In a study of patients with urinary tract carcinomas, researchers found that necrosis tended to be more common in larger tumors. The presence of necrosis in a tumor may provide doctors with a tool for predicting how aggressively the tumor is growing.Learn More
Cancer spreads through a process that involves the invasion of blood vessels and lymph nodes near a tumor, according to the American Cancer Society. The ability of cancer to spread successfully depends on a number of factors, and not all cancer cells can metastasize, or spread.Full Answer >
The chance of recovery for those diagnosed with esophageal cancer depends on the stage of the cancer, the size of the tumor and the patient's general health. The earlier the cancer is found, the better the patient's prognosis, according to Cancer.gov.Full Answer >
Stage III lung cancer is cancer that has progressed to the point that the tumor is difficult or impossible to remove through surgery, according to the American Society of Clinical Oncology. The tumor may have spread to a nearby organ or to the lymph nodes around the chest.Full Answer >
Brachytherapy, also called internal radiation therapy, is a procedure in which radioactive implants are inserted into the body or in or near a tumor, states Mayo Clinic. This type of radiation therapy allows doctors to give high doses of radiation to specific areas of the body.Full Answer >