Symptoms of the BK virus may include abnormal or declining renal allograft function, glomerular crescents, gradual rise in creatinine with properties that can mimic rejection, acute tubular necrosis and hemorrhagic cystitis, according to a study published in the Clinical Journal of the American Society of Nephrology. Some patients may also experience interstitial fibrosis, interstitial nephritis or chronic allograft nephropathy.
Patients might notice discolored urine, difficulty urinating, painful urination or seizures, according to Drugs.com. Fever, weakness and muscle pain are also possible symptoms.
The BK virus is a type of DNA virus that may occur following a kidney transplant. This virus is generally latent in the urinary tract and kidneys. For some people, it may reactivate and then begin to replicate. Several factors play a role in this when it comes to kidney transplant patients, such as antiviral immune function, how the person's immunosuppressant medications affect them and how much of the virus is present.