According to the Mister Glue website, Super Glue is not the best choice for repairing an air mattress because it lacks flexibility. However, industrial options, such as Mister Glue, are formulated to maintain flexibility and can be used to repair an air mattress.
The first step to patching an air mattress leak is to find the hole. Running water over the air mattress sometimes helps to find the hole, as does pressing gently on the mattress and listening for the escaping air. The hole can then be repaired using the specialized glue and a patch from a bicycle repair kit or one made of duct tape.