A dog becomes sleepy within 60 minutes from administration of a properly sized dose of Benadryl, according to AZVets.com. Peak levels of the active ingredient diphenhydramine are found in blood circulation within one to five hours, as noted in The Merck Veterinary Manual.Know More
Proper dosage of Benadryl is 2 to 4 milligrams per kilogram of pet weight, as prescribed by The Merck Veterinary Manual. This agrees with the simple rule of 1 milligram per pound recommended by AZVets.com and DoseMyPet.com. As an example, a 30-pound dog should be administered 30 milligrams of Benadryl in a proper dosage.
Some over-the-counter products containing Benadryl also contain other medications that are toxic to canines, including acetaminophen or pseudoephedrine. AZVets.com recommends checking labels closely and obtaining the advice of a veterinarian before administering any drug to a dog.Learn more about Veterinary Health
Common side effects of Benadryl in canines include the presence of dry mouth, a loss or decrease in appetite with or without vomiting, diarrhea and a decrease in urine according to PedMD. Benadryl has been known to react with other prescription medications like amitraz, furazolidon and epinephrine. Special precautions must be taken when administering Benadryl, especially to pregnant canines and canines with heart diseases or high blood pressure.Full Answer >
The lethal dose of diphenhydramine, the generic name of Benadryl, varies significantly from person to person because of differences in weight and metabolism. There have been cases of people experiencing overdose symptoms with 500 milligrams of diphenhydramine and some cases where overdose is as high as 2,800 milligrams.Full Answer >
A single dose of Diphenhydramine hydrochloride, commonly known as Benadryl, is active in the body for between four and six hours on average. The drug is almost completely excreted from the body within 24 hours, as explained by Drugs.comFull Answer >
An oral dose of Benadryl reaches peak blood concentrations 2 to 3 hours after consumption, and the effects usually last for 4 to 6 hours, reports the National Highway Traffic Safety Administration. WebMD suggests taking an oral dose of Bendryal about 30 minutes before bedtime, if the drug is being used as a sleep aid, or right before traveling overseas, if the drug is being used for motion-sickness.Full Answer >