Trazodone is a drug that is prescribed by a doctor for depression and anxiety that is associated with depression. This medicine needs to be carefully monitored by a doctor. Trazodone has many side effects, such as suicidal thoughts, that can be serious. The dosage is usually pretty low. It is usually prescribed once a day. The length of time Trazodone stays in your system is about twenty four hours. This medicine should not be stopped unless directed by a doctor.