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It depends on your design style - bottom-up or top-down. In a bottom-up design style (which is the most common) you are designing the block before you design the top-level that assembles
http://www.edaboard.com/thread133011.html
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Eddington : Synthesis is logic-level decisions and optimization. High-level synthesis is architectural-level optimization that takes a behavioral description and brings it down to
http://chipdesignmag.com/sld/blog/2009/12/17/exper...
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