How Does Paracetamol Work in the Body?


Paracetamol is generally considered to be a weak inhibitor of the enzyme cyclooxygenase-2 (COX-2). This enzyme is important in the synthesis of prostaglandins (PG), so by inhibiting the action of COX-2, paracetamol causes a decrease in PG production. Prostaglandins are important mediators of inflammation, and their release has many effects including the sensitisation of nerve cells to pain, and a direct effect on the hypothalamus in the brain resulting in fever.
1 Additional Answer Answer for: how does paracetamol work in the body
Acetaminophen (oral/rectal)
ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have More »
Q&A Related to "How Does Paracetamol Work in the Body"
It Dissolves.
Paracetamol, known in the United States as acetaminophen, is commonly known under the brand name Tylenol in the United States, and under the brand name Panadol in the United Kingdom
Overdoses of paracetamol can cause fatal liver
Paracetamol has a half-life of 1-4 hours, which means that after this time the concentration of paracetamol in your body will generally be half of what it was at the beginning. So
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