The half-life for Wellbutrin is 20 hours. This means that just one dose will stay in a person's system for more than a day. If a person takes it regularly then traces of the medication can stay in the system for several weeks to over a month.
Wellbutrin is a common medication used to treat depression. The main ingredient in this medication contain metabolites that can last for as long as 37 hours in the body. Wellbutrin itself stays in your system for 5 to 8 days.