Negative Effects of Christopher Columbus?

Answer

The negative effects of Christopher Columbus included the dangerous journey around the world where many of those traveling with him as part of his crew had perished during the voyage. Once arrived, the ailments were introduced to the native Americans amongst a few other negative effects. Syphilis was one deadly disease which was brought to America during the voyage and the native Americans had no antibodies for it whatsoever, which led to severe sicknesses with little possibility of recovery.
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