What does the sign with the letters "HC" on a highway mean?

Answer

A highway sign with the letters "HC" on it designates a route for vehicles transporting hazardous cargo. A similar sign with the "HC" circled in red and crossed with a diagonal red bar means that hazardous cargo is not allowed.

Hazardous cargo signs vary from state to state. In some states, an "HM," standing for hazardous materials, is used instead of an "HC." In most cases, the sign features black letters on a white square background. When hazardous cargo is allowed, the "HC" or "HM" may be surrounded by a green circle. The red circle with a strike-out bar is the standard sign designation for something that is not allowed.

Reference:
Q&A Related to "What does the sign with the letters "HC" on..."
A road sign with the black letters "HC" inside a green circle indicates a hazardous
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"Hazardous Cargo. It marks the routes that trucks carrying hazardous materials (such as caustic chemicals) are required to take, usually around instead of through the center
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A road sign with the black letters "HC" inside a green circle indicates a hazardous cargo route. Drive safely! report this answer. Updated on Thursday, February 02 2012
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What does "hc" mean on I highway sign? I saw this in ohio. Some with a red x through it,
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