When an ovarian cysts bursts, most women will experience pain on the lower abdomen to the pelvic area. The level of pain felt by each person is usually affected by what happens when the ovarian cyst bursts. This sharp pain is caused by the irritation of the inside layer of the peritoneal cavity called the peritoneum. The peritoneum can be irritated by either blood or the filling of the cyst. The cyst may contain a high concentration of prostaglandins, which may possibly cause irritation and lead to more pain to women with ovarian cysts.