What is the definition of myogenic activity?


Myogenic activity is rhythmic contraction of smooth or cardiac muscle, which is independent of nervous stimulation or neural input. Muscular contraction, during myogenic, activity is initiated and maintained automatically. Myogenic activity is related to the myogenic gene, and emanates from myocyte cells. Myogenic activity within resistance arteries play the role of regulating the flow of blood into body organs, through the dilation and constriction mechanisms.

Myogenic activity is often initiated by changes in posture and the associated alterations in blood pressure. Changes in transmural pressures outside blood vessels also initiate myogenic activity. Local regulatory mechanisms and adjustments are attributed to the initiation of myogenic activity. Sometimes spontaneous myogenic activity is associated with the movement of calcium and sodium ions along their concentration gradients. The myogenic mechanism is a reflex response to pressure change stimuli.

The presence of vasodilator compounds, such as histamine and bradykinin, within smooth muscles, stimulate myogenic activity. The auto-regulation mechanism during myogenic activity is common within the smooth muscles of the stomach. The myogenic activity of the cardiac muscles make the heart to operate without the stimulation of central nervous system nerves. Complicated medical procedures are used to initiate the heart's myogenic activity during medical emergencies related to heart failure.

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