What can cause a toe to have numbness and tingling?

Answer

According to WebMD, numbness and tingling in a toe can be caused by nerve damage from repetitive stress injuries, infections and systemic diseases. Persistent tingling and numbness should be promptly evaluated by a doctor.

Numbness and tingling caused by nerve damage is called peripheral neuropathy. This condition often gets worse over time and results in decreased mobility. Early identification and treatment reduces the risk of consequences resulting from this condition.

Infections that can cause numbness and tingling in a toe include shingles, herpes simplex, Lyme disease and HIV/AIDS. Notify the doctor if the toe tingling and numbness are accompanied by swelling, itching, fever, rash or other infection related symptoms.

A doctor can also perform tests for systemic diseases such as rheumatoid arthritis and lupus.

Reference:
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