Topic: Alkylating Agents
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What is al·kyl·at·ing agents?
( ăl'kə-lā'tĭng ) n. Any of various highly reactive chemical compounds that bond with various nucleophilic groups in nucleic acids and proteins and cause mutagenic, carcinogenic, or cytotoxic effects. Read More »
Source: http://www.answers.com/topic/alkylating-agent
What is the mechanism of action of alkylating agents?
Form covalent bonds with DNA, including cresslinks, thus inducing strand breaks. Read More »
Source: http://www.angelfire.com/sc3/toxchick/molbiocancer/molbiocancer24...
What is an Alkylating agent?
An alkylating agent is a compound that substitutes an alkyl group, CnH2n+1, for an active hydrogen atom in an organic compound. All of the alkylating agents form strong electrophiles through the formation of carbonium ion intermediates . Th... Read More »
Source: http://www.atlanticanalytical.com/pharmaceutical/alkylating_agent...
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Alkylating Agents
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a´jent adrenergic blocking agent one that inhibits response to sympathetic impulses by blocking the alpha (alpha-adrenergic blocking a.) or beta (beta-adrenergic blocking a.) receptor sites of effector organs. adrenergic neuron blocking ag...
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Source: http://medical-dictionary.thefreedictionary.com/alkylating+agent
