Topic: Immunoglobulin Gene Rearrangement
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What are the gene rearrangements
Gene rearrangements are structural alterations of a chromosome that... ...MORE... Read More »
Source: http://www.chacha.com/question/what-are-the-gene-rearrangements
how can genes become rearranged?
Any rearrangement within a gene is a mutation, and such rearrangement is usually due to a random genetic accident. The mutation can be harmless and simply add to the variation within an organism's genome, or it can be harmful with dire cons... Read More »
Source: http://www.answers.com/topic/how-can-genes-become-rearranged
How can a chromosomal rearrangement cause an increase in the expr...
The gene could be moved behind a stronger promoter, the gene could be duplicated, occasionally changes in the 3' and 5' UTRs can result in increased mRNA stability. Chromosomal rearrangement could also influence levels of enhancers and repr... Read More »
Source: http://wiki.answers.com/Q/How_can_a_chromosomal_rearrangement_cau...
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Answers to Other Common Questions
(Life Sciences & Allied Applications / Biochemistry) any of five classes of proteins, all of which show antibody activity. The most abundant ones are immunoglobulin G (IgG) and immunoglobulin A (IgA)
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Source: http://www.thefreedictionary.com/immunoglobulin+genes
The introduction of a stop codon, or a reading frame shift. If it is the first attempt, an attempt is made to rearrange the second allele. If both alleles have been rearranged nonproductively, the B cell undergoes apoptosis.
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Source: http://www.bio.umass.edu/micro/immunology/exams/x2-00540.htm