Topic: Pemphigoid Gestationis
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What causes pemphigoid gestationis?
Pemphigoid gestationis is an autoimmune blistering disease, which basically means that an individual's immune system starts reacting against his or her own tissue. Immunoglobulin type G (IgG) autoantibodies (known as the PG factor) cause th... Read More »
Source: http://dermnetnz.org/immune/pemphigoid-gestationis.html
What is pemphigoid gestationis?
Pemphigoid gestationis is a rare pregnancy-associated autoimmune skin disease that is characterised by an itchy rash that develops into blisters. It is most common during the second and third trimesters of pregnancy. It is also known as her... Read More »
Source: http://dermnetnz.org/immune/pemphigoid-gestationis.html
What are the signs and symptoms of pemphigoid gestationis?
Most patients present with an intensely itchy hive-like rash during mid to late pregnancy (13 to 40 weeks gestation). Initially there are itchy red bumps around the belly button Within days to weeks, the rash spreads to other parts of the b... Read More »
Source: http://dermnetnz.org/immune/pemphigoid-gestationis.html
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Pemphigoid Gestationis
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Pemphigoid gestationis is quite rare. It has been estimated to affect 2 out of every 100,000 pregnancies. There is also a racial difference with Caucasians being more affected than black women.
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Source: http://www.pregnancybliss.com/pemphigoid_gestationis.html
Itching is common and often starts around the umbilicus (belly button) during mid to late pregnancy (13 to 40 weeks gestation). Itching may be followed by a rash with large red inflamed areas of skin and then later blisters can develop.
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Source: http://www.eadv.org/patient-corner/leaflets/eadv-leaflets/pemphig...
Diagnosis requires a skin sample (biopsy) and/or a blood for laboratory tests. Usually the appearance and behaviour of the rash is very typical but in early disease without blisters the rash can look reminiscent of other skin diseases such ...
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Source: http://www.eadv.org/patient-corner/leaflets/eadv-leaflets/pemphig...
The primary aim of treatment is to relieve itching, prevent blister formation and treat any secondary infection. It is also important during pregnancy to use treatments that are as safe as possible for both mother and baby. Topical steroid ...
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Source: http://www.eadv.org/patient-corner/leaflets/eadv-leaflets/pemphig...
Reassure the woman that the prognosis is good with treatment, but that the condition is likely to have exacerbations and remissions throughout the pregnancy (and will probably flare up at childbirth). Advise that the baby may be small for i...
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Source: http://www.cks.nhs.uk/itch_in_pregnancy/management/scenario_itch_...
There is often an urticarial rash with wheals (like hives from nettles) and large raised red patches (plaques) commonly occurring on the trunk, back, buttocks and limbs. The face, scalp and mucous membranes (mouth and genital area) are usua...
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Source: http://www.eadv.org/patient-corner/leaflets/eadv-leaflets/pemphig...
