Topic: Statins and Myopathy
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Answers to Common Questions
How to Prevent Or Treat Statin Myopathy
Statin medications such as Lipitor and Crestor are among the most commonly prescribed medications in the world. Statins have been proven to reduce the incidence of both strokes and heart attacks as well as prolong patient life. Despite the ... Read More »
Source: http://www.ehow.com/how_5517710_prevent-treat-statin-myopathy.htm...
WHAT IS STATIN-RELATED MYOPATHY?
Muscle disease related to drugs called statins. Read More »
Source: http://answers.yahoo.com/question/index?qid=20110630132640AAiwqVo
How do the statins compare in their propensity for inducing myopa...
First, we have to acknowledge that despite the clinical importance of statin-induced myopathy, we understand very little about its causes, which makes it hard to develop good treatments or preventive strategies. Read More »
Source: http://www.medscape.com/viewarticle/481357%3Frss
More Common Questions
Answers to Other Common Questions
Symptoms include muscle aches, heaviness, stiffness and cramping. Symptoms occur mostly in the thighs and calves, although about one in four of those affected may feel generalized pain. Symptoms may also include:
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Source: http://www.myoptumhealth.com/portal/Information/item/Statins+and+...
If a patient's history, physical examination, and creatine kinase measurements show features of statin induced myopathy, first line management is to stop statins, observe symptoms, and monitor creatine kinase. A repeat challenge with statin...
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Source: http://www.natap.org/2008/HIV/112108_02.htm
The mechanism of statin induced myopathy is unknown. One proposal is that impaired synthesis of cholesterol leads to changes in the cholesterol in myocyte membranes and changes the behaviour of the membrane.8 However, inherited disorders of...
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Source: http://www.natap.org/2008/HIV/112108_02.htm
Symptoms of statin induced myopathy include fatigue, muscle pain, muscle tenderness, muscle weakness, nocturnal cramping, and tendon pain. The muscle symptoms tend to be proximal, generalised, and worse with exercise. In a small retrospecti...
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Source: http://www.natap.org/2008/HIV/112108_02.htm
The clinical spectrum of statin induced myopathy includes myalgia, myositis, rhabdomyolysis, and an asymptomatic increase in the concentration of creatine kinase. Muscle related adverse events can be difficult to describe because the termin...
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Source: http://www.natap.org/2008/HIV/112108_02.htm
Evidence from well designed randomised controlled trials shows that myopathy correlates most closely with dose of statins and is independent of reductions in low density lipoprotein cholesterol.13 Several risk factors have been proposed, ma...
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Source: http://www.natap.org/2008/HIV/112108_02.htm