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Synonyms
hand·cuff (hănd́kŭf́)

noun 

A restraining device consisting of a pair of strong, connected hoops that can be tightened and locked about the wrists and used on one or both arms of a prisoner in custody; a manacle. Often used in the plural.

transitive verb: -cuffed, -cuff·ing, -cuffs. 

  1. To restrain with or as if with handcuffs.
  2. To render ineffective or impotent. See synonyms at hamper1