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Synonyms
brain (brān)

[Middle English, from Old English brægen.]

noun 

    1. The portion of the vertebrate central nervous system that is enclosed within the cranium, continuous with the spinal cord, and composed of gray matter and white matter. It is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs. It is also the seat of consciousness, thought, memory, and emotion.
    2. A functionally similar portion of the invertebrate nervous system.
    1. Intellectual ability; mind: a dull brain; a quick brain.
    2. Intellectual power; intelligence. Often used in the plural: has brains and good looks. See synonyms at mind
  1. A highly intelligent person.
  2. The primary director or planner, as of an organization or movement. Often used in the plural.
  3. The control center, as of a ship, aircraft, or spacecraft.

transitive verb: brained, brain·ing, brains. 

Slang
  1. To smash in the skull of.
  2. To hit on the head.

idioms

beat (one's) brains (out)
Informal To exert or expend great mental effort: She beat her brains out during the examination.
on the brain
Obsessively in mind: The coach has winning on the brain.
pick (someone's) brain
To explore another's ideas through questioning.
rack (one's) brain
To think long and hard: I racked my brain for hours trying to recall her name.