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affliction

affliction - noun

  1. A state of physical or mental suffering: agony, anguish, distress, hurt, misery, pain, torment, torture, woe, wound, wretchedness. See happy.
  2. The condition of being sick: disorder, illness, indisposition, infirmity, sickness. See health.
  3. Something hard to bear physically or emotionally: burden, cross, trial, tribulation. See heavy. over.
  4. A cause of suffering or harm: bane, curse, evil, ill, plague, scourge, woe. See help.