North Dakota State University defines a DNA probe as a small piece of nucleic acid (typically single-stranded DNA) that is used to detect complementary stretches of DNA. DNA probes used in hybridization experiments are labeled so that they can be visualized.Know More
As Wikipedia explains, DNA probes are typically labeled with either radioactive or fluorescent bases. It is more common to use fluorescent DNA probes because a variety of different fluorescent wavelengths can be chosen, which allows scientists to hybridize more than one probe to a given sample at a time.
According to "Human Molecular Genetics," DNA probes can be used for a variety of different molecular biology techniques. When used with a Southern or northern blot, DNA probes can be used to detect size fragments of a gene or other segment of DNA in question.
DNA probes can also be used for fluorescence in situ hybridization techniques, in which chromosomes are denatured on microscope slides. This method allows for the detection of larger chromosomal aberrations, including broken or fused chromosomes. Chromosome painting techniques utilize in situ hybridization to paint metaphase chromosomes different colors, which makes chromosome mapping easier. This technique can also be used to detect chromosome sequences that have been conserved between different species.Learn more about Molecular Biology & DNA
DNA replication is a process in which DNA is duplicated so that it can be integrated into a new cell during cell division. The process produces two identical replicas of the DNA molecule from one original DNA molecule. It occurs in every living organism on Earth, allowing parental generations to pass on genes to their offspring.Full Answer >
DNA, or deoxyribonucleic acid, is a chain that is made up of smaller parts known as nucleotides. These nucleotides are then made up of three different parts of nucleotides: the sugar group, the phosphate group and a group of four different nitrogen bases, which are adenine (A), cytosine (C), guanine (G) and thymine (T).Full Answer >
The subunit of DNA is called a nucleotide. A nucleotide is the basic subunit in a nucleic acid and consists of a pentose sugar, a phosphate and a heterocyclic amine.Full Answer >
RNA, or ribonucleic acid, is responsible for the transfer of genetic information to cell components called ribosomes. DNA, or deoxyribonucleic acid, is responsible for the transfer and duplication of long-term genetic information during cell reproduction. They are both essential to the process of creating new organisms and the biological functions of organisms.Full Answer >