The enzyme DNA helicase unzips the DNA double helix to allow it to replicate. DNA helicase has a rotation speed of 10,000 rotations per minute and moves ahead of the replication fork. It continuously unwinds the DNA strands to allow DNA polymerase to attached new nucleotide strands.
DNA helicase is a hexameric ring structure of six subunits. It unzips the double helix by breaking down the hydrogen bonds holding the DNA strands together. After being unzipped, the strand with the 3' -OH group becomes the leading strand, which can be replicated immediately. The strand with the 5' -OH group is the lagging strand, and it is replicated later in a process known as discontinuous replication.Learn More
The function of DNA polymerase is to replicate, proofread and repair DNA. Several DNA polymerases exist, but DNA polymerase I, or Pol I, and DNA polymerase III, or Pol III, are the main ones involved in DNA replication.Full Answer >
"The Race for the Double Helix" is a 1986 made-for-television movie telling the story of the 1950s competition to discover the structure of DNA. It is based on the events described in James D. Watson's book "The Double Helix."Full Answer >
The powerful enzyme DNA helicase unwinds the double strands of DNA by breaking the bonds between each of the complementary bases. These bases are held together by strong hydrogen bonds, but in breaking these, DNA helicase creates two single-stranded DNA molecules.Full Answer >
DNA polymerases is the enzyme that catalyzes DNA synthesis, but it is different from RNA polymerases. This particular type of polymerases have specific conditions and requirements that must be met for them to be produced. Without these enzymes, the nucleotides that are the building blocks of DNA cannot be made.Full Answer >