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What is pedigree analysis?

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Pedigree analysis is the process of examining a pedigree to determine the pattern of inheritance for a trait. Pedigrees are often used to determine if a trait is dominant or recessive.

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Dominant traits are passed on to a child from at least one affected parent. This results in a trait that does not skip generations. Recessive traits can be masked by dominant genes. This means that both parents can be carriers and have an affected child, resulting in a recessive trait that can skip generations.

Pedigrees show the presence or absence of a trait through several generations of a family by using a series of symbols to represent family relationships, with squares representing males and circles representing females. A marriage is shown by connecting two symbols with a horizontal line. When children result from a union a vertical line drops down from the couple, and the children are represented below the couple. This results in an diagram with successive generations occurring in a vertical pattern, with the oldest generation at the top of the pedigree and the youngest generation at the bottom. The presence of a trait is indicated by a shaded circle or square, while the absence of a trait is indicated by a clear symbol.

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