Q:

Where does testosterone come from?

A:

Quick Answer

While a small percentage of testosterone is made in the adrenal glands, about 95 percent of testosterone is produced in male testicles. The hypothalamus detects a testosterone deficiency and sends a gonadotropin-releasing hormone to the pituitary gland, which then sends two hormones to the testicles that stimulate testosterone production.

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Full Answer

Testosterone is a 19-carbon steroid hormone made from cholesterol. Pure or free testosterone, unbound to proteins, makes up about 2 to 3 percent of total testosterone levels. In this form, it is able to enter cells and activate receptors.

Testosterone bound to sex-hormone-binding-globulin, a protein produced in the liver, is biologically inactive. It does not provide any of the benefits of pure testosterone, but makes up about 40 to 50 percent of the total testosterone levels. The remainder of testosterone is bound to albumin, another protein produced in the liver. Although albumin-bound testosterone is also inactive, the bond between protein and testosterone is weak, and can be broken to create free testosterone.

A male begins producing testosterone about seven weeks after conception. It aids in forming male genitals in the womb, and surges in the body during puberty. Testosterone drives the growth of body hair, plays a role in behaviors such as aggression or dominance, and can spark competitiveness. Low testosterone can result in a loss of confidence or lack of motivation.

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Related Questions

  • Q:

    Where is testosterone produced?

    A:

    According to WebMD, testosterone is produced primarily by the testes, the main male organs of reproduction, though it is also produced in small amounts by women's ovaries. Testosterone production in the testes is conditioned by multiple factors that are mainly related to the production and maintenance of other hormones throughout the body.

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  • Q:

    Where is testosterone made in the body?

    A:

    According to MedicineNet, most of men's testosterone is produced in their testicles. Much lower amounts are also made in women's ovaries. Testosterone is needed in men for the development of secondary sex characteristics, such as chest hair and voice deepening.

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  • Q:

    What is the function of the adrenal gland?

    A:

    The adrenal glands are responsible for creating hormones, including cortisol, aldosterone, androgen, noradrenaline and adrenaline. Each person has two adrenal glands, and one is located on the top of each kidney.

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  • Q:

    What is Addison's disease?

    A:

    Addison's disease occurs when the adrenal glands don't produce sufficient quantities of cortisol and aldosterone. The adrenal glands are part of the endocrine system, which regulates metabolism, mood, growth and how a person responds to stress.

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