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Alternate Name(s): Glucuronyl transferase deficiency (type I Crigler-Najjar); Arias syndrome (type II Crigler-Najjar) ... Crigler-Najjar syndrome is an inherited disorder in which bilirubin (a substance made by the liver) cannot be changed into its water-soluble form, bilirubin glucuronide. This causes jaundice (yellow discoloration of skin and eyes) and organ ...
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Crigler-Najjar syndrome - Wikipedia, the free encyclopedia
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Overview: Crigler-Najjar syndrome (CNS) is a rare autosomal recessive disorder of bilirubin metabolism. Two distinct forms have been described, as follows: type 1 and type 2. Type 1 Crigler-Najjar syndrome, first described in 1952 by Crigler and ... ... Crigler-Najjar syndrome is a much rarer disorder, with only a few...
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Article describes Crigler-Najjar syndrome, its symptoms, diagnosis, and treatment. ... Crigler-Najjar syndrome is an inherited disorder of bilirubin metabolism. It is an autosomal recessive disorder, meaning that an individual needs to receive two copies of the defective gene, one from each parent, in order to develop...
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Crigler-Najjar syndrome: A familial form of congenital hyperbilirubinemia associated with severe disorders of the central nervous system and resembling kernicterus (degeneration of the basal ganglia). Also known as: Arias’ syndrome. ... Hyperbilirubinaemia in newborn in Crigler-Najjar syndrome is called Najjar-Crigler icterus.
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Crigler-Najjar syndrome - Overview, Crigler-Najjar syndrome is a very rare inherited d... ... Crigler-Najjar syndrome is caused by an abnormal gene. The gene fails to make the enzyme that normally converts bilirubin into a form that can easily be removed from the body.
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Crigler-Najjar Syndrome information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. ... Symptoms of Crigler-Najjar Syndrome...
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Signs of Crigler-Najjar syndrome, type 2 including medical signs and symptoms of Crigler-Najjar syndrome, type 2, symptoms, common medical issues, duration, and the correct diagnosis for Crigler-Najjar syndrome, type 2 signs or Crigler-Najjar syndrome, type 2 symptoms. ... Symptoms of Crigler-Najjar syndrome, type 2...
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