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Nat Rev Drug Discov. 2014 Jun;13(6):419-31. doi: 10.1038/nrd4309. Epub 2014 May 16. Lessons learned from the fate of AstraZeneca's drug pipeline: a ...


May 19, 2014 ... All of these categories of failure can be ascribed to a breakdown in scientific management and leadership. Scientists will naturally display ...


May 16, 2014 ... Given the wealth of scientific and technological advances in recent decades — ranging from ultra-high-throughput screening to the.


Everyone is most interested in projects that succeed. The challenge is that most projects in Bio/pharmaceutical R&D do not succeed. Figure 1 outlines the high ...


E Lee, S Ryan, B Birmingham, J Zalikowski, R March, H Ambrose, ... Clinical Pharmacology & Therapeutics 78 (4), 330-341, 2005. 364, 2005. Lessons learned ...