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Cullin-RING Ligases as Attractive Anti-cancer Targets - NCBI


Cullin-RING ligases (CRLs) are the largest family of E3 ubiquitin ligases that promote the ubiquitination of about 20% of cellular proteins doomed for ...... [62] Singh A, Misra V, Thimmulappa RK, et al. .... [96] Tan M, Gallegos JR, Gu Q, et al.

Small RING Finger Proteins RBX1 and RBX2 of SCF E3 Ubiquitin ...


Tetrameric SCF (Skp1–cullin/Rbx–F-box protein) E3 ubiquitin ligase, also ...... Tan M, Gallegos JR, Gu Q, et al. ... Nishitani H, Sugimoto N, Roukos V, et al.

Radiosensitization of Cancer Cells by Inactivation of Cullin-RING E3 ...


Oct 1, 2012 ... Cullin-based RING ligases (CRLs) are the largest family of E3 ligases that are ..... Consistently, using high-throughput screening, Chen et al. recently identified an agent, ..... Tang W, Li Y, Yu D, Thomas-Tikhonenko A, Spiegelman VS, Fuchs SY. ... Tan M, Gallegos JR, Gu Q, Huang Y, Li J, Jin Y, Lu H, Sun Y.

CDK-1 and Two B-Type Cyclins Promote PAR-6 Stabilization ... - Plos


Feb 6, 2015 ... Furthermore, the activity of the cullin CUL-2 was required ...... Hyenne V, Desrosiers M, Labbé JC (2008) C. elegans Brat homologs regulate PAR protein- .... Kraemer B, Crittenden S, Gallegos M, Moulder G, Barstead R, et al.

The lin-41 RBCC Gene Acts in the C. elegans Heterochronic ...


... L1 stage (Feinbaum and. Ambros, 1999) by the lin-4 regulatory RNA (Lee et al. , .... We examined lateral hypodermal seam cells (V cells and were fertile while ...

Download PDF - Plos


Mar 28, 2013 ... Citation: Burger J, Merlet J, Tavernier N, Richaudeau B, Arnold A, et al. ... Many E3 enzymes are nucleated around cullin scaffold subunits, ...... Crittenden SL, Bernstein DS, Bachorik JL, Thompson BE, Gallegos M, et al. ... proliferation vs. meiotic entry decision in the Caenorhabditis elegans germ line.

APA Style Blog: Et al.: When and How?


Feb 4, 2011 ... Third on the list is the usage of et al. Given the level of detail in these style rules, it's no surprise that many find them challenging. Here are three ...

Et Al and Et Ux: Two Latin Phrases You Need to Know - Amy ...


Jun 19, 2015 ... Sometimes the clerk who created the index didn't make an entry for each person. Instead, he could have used two common Latin phrases: et al.

et al. - Wiktionary


From Latin, abbreviation of et (“and”) and alii (“others”) (English: et alii) and its ... However, in lists of authors of a published work, et al. is still regularly used.

Caenorhabditis elegans p97 controls germline-specific sex ...


CUL-2 belongs to the cullin family of E3 ubiquitin ligases and CUL-2 complexes consist of ..... 5B), which is consistent with a previous report (Starostina et al., 2007). ..... Crittenden, S. L., Bernstein, D. S., Bachorik, J. L., Thompson, B. E., Gallegos, M., Petcherski, A. G., .... Praitis, V., Casey, E., Collar, D. and Austin, J. ( ...

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Cullins and Cancer - NCBI - National Institutes of Health


In this review, we will discuss cullin complexes and their substrates, the regulatory pathways that affect .... Noubissi et al. showed that β-catenin signaling activates the expression of mRNA-binding protein CRD-BP ..... Tan M, Gallegos JR, Gu Q, et al. ... Tang W, Li Y, Yu D, Thomas-Tikhonenko A, Spiegelman VS, Fuchs SY.

Direct protein–protein interaction between the intracellular domain ...


TRA-2A (Okkema and Kimble 1991; Kuwabara et al. 1998). Genetic evidence .... culinizing effect on somatic development, whereas the allele encoding the ...

Inactivation of SAG E3 Ubiquitin Ligase Blocks Embryonic Stem Cell ...


Nov 15, 2011 ... We next used one representative pair of mES cells (AB1/Sag<sup>−/−</sup>vs. AB2/Sag<sup>+/+</sup>) to ..... Tan M, Gallegos JR, Gu Q, Huang Y, Li J, et al. (2006) ...