Osteogenesis imperfecta (OI), also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It results in bones that break easily . The severity may be mild to severe. Other symptoms may include a blue tinge to the whites of the eye, short ... The blue-gray color of the sclera is due to the underlying choroidal veins ...
Jul 10, 2015 ... However, the severity of the disease varies greatly. The classic symptoms include : Blue tint to the whites of their eyes (blue sclera); Multiple ...
Blue sclerae have been reported. ... Bluish sclerae are sometimes present. .... Brittle cornea syndrome: recognition, molecular diagnosis and management.
Aug 13, 2015 ... Common causes of Blue sclerae symptom from a list of 47 total causes of ... The offical US government definition of a "rare" disease is one that ...
What are the symptoms of osteogenesis imperfecta (OI)? ... Hearing loss in some cases; Blue sclera (whites of the eyes); Easy bruising; Mild delay in ... People with OI are more vulnerable to lung problems, including asthma and pneumonia.
Aug 2, 2011 ... Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at ... Blue tint to the whites of their eyes (blue sclera); Multiple bone ...
Collagen synthesis diseases were considered. Congenital defects in collagen synthesis cause thinning of the sclera, which causes a bluish hue on examination .
Apr 7, 2017 ... It can be associated with autoimmune disorders. Learn about ... Scleritis is an inflammation of the white portion of the eye, the sclera. Scleritis is ...
Dec 18, 2008 ... Diffuse blue sclera results from thinning of the sclera. This might be ... Diagnosis and treatment of any underlying disease is very important.