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Osteogenesis imperfecta (OI), also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It results in bones that break easily . The severity may be mild to severe. Other symptoms may include a blue tinge to the whites of the eye, short ... The blue-gray color of the sclera is due to the underlying choroidal veins ...


Jul 10, 2015 ... If you have 1 copy of the gene, you will have the disease. Most cases of OI are inherited from a parent. However, some cases are the result of ...


Aug 13, 2015 ... This information shows the various causes of Blue sclerae, and how common these diseases or conditions are in the general population.


Aug 2, 2011 ... Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at ... Blue tint to the whites of their eyes (blue sclera); Multiple bone ...


Collagen synthesis diseases were considered. Congenital defects in collagen synthesis cause thinning of the sclera, which causes a bluish hue on examination .


Jan 25, 2017 ... Blue sclera is a condition of the eyes in which the whites of the eyes are a bluish color. This eye condition is a risk factor for many other eye diseases like ... Protect Your Eyesight: Warning Signs of Common Eye Conditions.


Blue sclerae have been reported. ... Bluish sclerae are sometimes present. .... Brittle cornea syndrome: recognition, molecular diagnosis and management.


What are the symptoms of osteogenesis imperfecta (OI)? ... Hearing loss in some cases; Blue sclera (whites of the eyes); Easy bruising; Mild delay in ... People with OI are more vulnerable to lung problems, including asthma and pneumonia.


Osteogenesis imperfecta (OI) is a disease that causes weak bones that break ... Muscle weakness; Sclera (whites of the eyes) that look blue, purple, or gray ...