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Esperion's Novel Approach To Lowering Cholesterol - Will It Be ...


Sep 5, 2013 ... Esperion has made great scientific advances in coming up with ETC-1002. However, great science doesn't assure medical success.

Beyond Statins: Providing an Alternative for LDL-C Lowering ...


Apr 9, 2014 ... Our Approach ... ETC-1002 is a novel, oral, once-daily small molecule therapy that we like to describe as a “statin for patients who can't tolerate a statin. ... the LDL-C lowering world, Esperion is uniquely positioned for success in one ... the headlines about the high cost of the new cholesterol lowering drugs.

The Future of Lipid Management: Novel Approaches for the At-Risk ...


Nov 10, 2014 ... Explore the use of PCSK9 inhibitors and other novel therapeutic agents to ... of patients with low levels of high-density lipoprotein cholesterol (HDL-C) ... To successfully earn credit, participants must complete the activity online during ... Credits will be tallied in your CME/CE Tracker and archived for 6 years; ...

The 3 Best Stocks for Investing in Cholesterol Drugs -- The Motley Fool


Apr 18, 2015 ... Statins' cholesterol-lowering ability and a growing global need for ... Targeting cholesterol in this manner is a novel approach, and results from Praluent's ... analysts think Repatha can split the market for PCSK9 drugs with Praluent. ... have cholesterol-fighting medicines awaiting FDA approval, Esperion ...

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Nov 30, 2015 ... Clarifying The Conversation Part III: Esperion Therapeutics, Inc. (NASDAQ: ... December 14, 2015 AdCom for Vytorin/Zetia label expansion will provide ... guide its approach to future labeling of other types of LDL-lowering agents such .... well as FDA voting members supported approval of these novel drugs ...

HDL Function, Dysfunction, and Reverse Cholesterol Transport - NCBI


Although high HDL-cholesterol levels are associated with decreased cardiovascular .... HDL function can be measured in several in vitro assays. .... The infusion approach was also successful in suppressing atherosclerosis progression in rabbits. ... Thus, antagonism of miR-33 may represent a novel approach to enhancing ...

Non-statin Treatments for Managing LDL Cholesterol ... - Medpace


effective, with a number of approaches aimed at this target. The most ... Table I. LDL cholesterol-lowering therapies: new drugs in development. General or ...



Jul 30, 2015 ... The use of words such as “may,” “might,” “will,” “should,” “expect,” “plan,” “ anticipate,” ... research and development programs, our ability to advance ETC- 1002 into, and successfully .... Adapted a novel mechanism based approach rather than .... ETC-1002 lowers hsCRP in patients with high cholesterol.

Questions Remain in Cholesterol Research | Medpage Today


Aug 15, 2014 ... It's well established that lowering LDL cholesterol reduces ... strategies for LDL lowering, noting the recent lack of success with CETP inhibitors torcetrapib and ... will be available soon for several novel therapeutic approaches that reduce ... Eli Lilly, Genzyme, Isis, Aegerion, Esperion, AstraZeneca, Omthera, ...

Esperion – Seeing the glass half full | Open Reading Frame


Nov 1, 2015 ... Even after reducing likelihood of success and stretching timelines, this is very ... by inhibiting the cholesterol biosynthesis pathway, but unlike statins it does not lead ... Esperion will shortly have the only P3 oral drug in development for ... novel and potentially groundbreaking approach for many diseases wit ...

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Understanding Key Pathways | Esperion Therapeutics


Understanding Cholesterol Lowering ... Esperion's founder, Dr. Roger Newton, co-discovered and helped lead the development of the most successful drug to ...

A farewell to statins – part one | Dr. Malcolm Kendrick


Nov 25, 2013 ... It is also interesting that LDL lowering agents, other than statins, have failed to ... - novel-approach-to-lowering-cholesterol-will-it-be-successful/ ...

Steven Nissen | Dr. Malcolm Kendrick


Dec 9, 2013 ... That can occur with high dose statins, and some people [who] say that they ... Nissen sell the results of these studies that a start-up company called Esperion, .... -novel-approach-to-lowering-cholesterol-will-it-be-successful/.