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Berberine--a novel approach to cholesterol lowering. - NCBI


Although low-density lipoprotein (LDL)-cholesterol lowering with the statins reduces the mortality and morbidity associated with coronary artery disease, ...

FDA Places Roadblock On Approval Path Of Novel Cholesterol Drug


Jun 30, 2016 ... Without the surrogate endpoint of LDL lowering the approval would be pushed back ... Esperion also announced that the CVOT, which will be known as ... Given the modest success of the PCSK9 inhibitors so far does it even ...

CardioBrief: Novel Cholesterol Drug Faces Long Delay | Medpage ...


Jun 30, 2016 ... Without the surrogate endpoint of LDL lowering, the approval would be pushed back to 2022 ... Esperion also announced that the cardiovascular outcomes trial, which will be known as Cholesterol Lowering via Bempedoic Acid, ... Given the modest success of the PCSK9 inhibitors so far, does it even matter ...

Understanding Key Pathways | Esperion Therapeutics


Understanding Cholesterol Lowering. At Esperion, we are leveraging our experience and understanding of key biological pathways to develop and ...

When it comes to PCSK9s, payers resisted — and sales flopped ...


Jan 10, 2017 ... These treatments, both novel ones and me-toos, are being met with payer ... scientific director at Discovery USA, predicts payers will continue to ... As a result, companies lost interest in investing in new approaches to lowering cholesterol. ... Esperion's bempedoic acid, an oral cholesterol-lowering treatment ...

The 3 Best Stocks for Investing in Cholesterol Drugs -- The Motley Fool


Apr 18, 2015 ... Statins' cholesterol-lowering ability and a growing global need for cholesterol- busting ... Targeting cholesterol in this manner is a novel approach, and results from ... Those clinical trial results could mean that the FDA will give the drug a green light ... 3: Esperion Therapeutics (NASDAQ:ESPR) -- ETC-1002

7 Tips to Fix Your Cholesterol Without Medication | The Huffington Post


Jan 29, 2011 ... The singular focus on treating cholesterol. ... At best this new “super cholesterol” drug will lower cholesterol numbers .... and pre-diabetes or metabolic syndrome can be successfully diagnosed and treated. ... For the vast majority of people this approach is better than simply taking a cholesterol medication.

CME Symposia - Cardiometabolic Health Congress


Good leadership skills are essential to build a successful practice. ... with elevated atherogenic cholesterol levels and statin intolerance based on safety and efficacy. ... Attendees will leave with the latest information on novel LDL lowering ... Managing Inflammation: A Novel Approach for Secondary Prevention of CVD Risks.

Cleveland Clinic Innovations - Success Stories


... CBLI) is an innovative biopharmaceutical company developing novel approaches to activate ... About the Company: Esperion is a pharmaceutical company focused on ... oral, low-density lipoprotein cholesterol (LDL-C) lowering therapies for the ... Healthcare data can span across a disparate ecosystem of employed and ...

A farewell to statins – part one | Dr. Malcolm Kendrick


Nov 25, 2013 ... It is also interesting that LDL lowering agents, other than statins, have ... /05/ esperions-novel-approach-to-lowering-cholesterol-will-it-be-successful/ .... Pfizer bought Esperion for a billion $ in order to protect Lipitor's 12 billion ...