Sep 5, 2013 ... Esperion has made great scientific advances in coming up with ETC-1002.
However, great science doesn't assure medical success.
Understanding Cholesterol Lowering ... Esperion's founder, Dr. Roger Newton,
co-discovered and helped lead the development of the most successful drug to ...
Nov 10, 2014 ... Explore the use of PCSK9 inhibitors and other novel therapeutic agents to ... of
patients with low levels of high-density lipoprotein cholesterol (HDL-C) ... To
successfully earn credit, participants must complete the activity online during ...
Credits will be tallied in your CME/CE Tracker and archived for 6 years; ...
Although high HDL-cholesterol levels are associated with decreased
cardiovascular .... HDL function can be measured in several in vitro assays. ....
The infusion approach was also successful in suppressing atherosclerosis
progression in rabbits. ... Thus, antagonism of miR-33 may represent a novel
approach to enhancing ...
effective, with a number of approaches aimed at this target. The most ... Table I.
LDL cholesterol-lowering therapies: new drugs in development. General or ...
Nov 30, 2015 ... Clarifying The Conversation Part III: Esperion Therapeutics, Inc. (NASDAQ: ...
December 14, 2015 AdCom for Vytorin/Zetia label expansion will provide ...
guide its approach to future labeling of other types of LDL-lowering agents such
.... well as FDA voting members supported approval of these novel drugs ...
Aug 15, 2014 ... It's well established that lowering LDL cholesterol reduces ... strategies for LDL
lowering, noting the recent lack of success with CETP inhibitors torcetrapib and ...
will be available soon for several novel therapeutic approaches that reduce ... Eli
Lilly, Genzyme, Isis, Aegerion, Esperion, AstraZeneca, Omthera, ...
Jul 30, 2015 ... The use of words such as “may,” “might,” “will,” “should,” “expect,” “plan,” “
anticipate,” ... research and development programs, our ability to advance ETC-
1002 into, and successfully .... Adapted a novel mechanism based approach
rather than .... ETC-1002 lowers hsCRP in patients with high cholesterol.
This activity will elucidate the PCSK9 pathway and the importance of LDL
receptor ... in the regulation of cholesterol homeostasis, and expert faculty will
summarize the ... Translating Genetic Discoveries into Novel Targets for Lipid
Management ... and Clinical Evidence for a New Therapeutic Approach to LDL-C
Dr Ajit Srivastava, Executive Director, Esperion Therapeutics, USA served as the
... Many renowned and accomplished professors, scientists and successful ... Dr
Newton is a co-discoverer of Lipitor, a drug that lower cholesterol and has helped
... Dr Newton also started a new company that focused on a novel approach of ...