Sep 5, 2013 ... Esperion has made great scientific advances in coming up with ETC-1002.
However, great science doesn't assure medical success.
Understanding Cholesterol Lowering ... co-discovered and helped lead the
development of the most successful drug to inhibit ... Bempedoic Acid (ETC-1002
), our novel, first-in-class, orally available, once-daily, ... Our Pathways Approach.
Lowering elevated LDL-C, a leading risk factor for cardiovascular disease,
remains a ... Elevated LDL-cholesterol (LDL-C or “bad cholesterol” ) is a
significant risk ... Statin therapy is effective but side effects and intolerance can
limit use for some ... Despite the success of statins for many patients, Esperion
believes there is a ...
Apr 18, 2015 ... Statins' cholesterol-lowering ability and a growing global need for cholesterol-
busting ... Targeting cholesterol in this manner is a novel approach, and results
from ... analysts think Repatha can split the market for PCSK9 drugs with Praluent
. ... 3: Esperion Therapeutics (NASDAQ:ESPR) -- ETC-1002
Nov 12, 2015 ... High cholesterol and lipid levels can significantly increase a person's risk ... with
lifestyle changes, medications, or a combination of these approaches. ...
However, the success of lipid lowering with lifestyle modification varies ...
Nov 25, 2013 ... It is also interesting that LDL lowering agents, other than statins, have ... /05/
esperions-novel-approach-to-lowering-cholesterol-will-it-be-successful/ .... Pfizer
bought Esperion for a billion $ in order to protect Lipitor's 12 billion ...
Nov 1, 2015 ... Even after reducing likelihood of success and stretching timelines, this is very ...
by inhibiting the cholesterol biosynthesis pathway, but unlike statins it does not
lead ... Esperion will shortly have the only P3 oral drug in development for ...
novel and potentially groundbreaking approach for many diseases wit ...
Jan 29, 2011 ... The singular focus on treating cholesterol. ... At best this new “super cholesterol”
drug will lower cholesterol numbers .... and pre-diabetes or metabolic syndrome
can be successfully diagnosed and treated. ... For the vast majority of people this
approach is better than simply taking a cholesterol medication.
Feb 22, 2015 ... Esperion's ETC-1002 is the only oral LDL-lowering in development with clear
efficacy in humans. ... At that point, Esperion will strike a licensing deal or get
acquired ... an 80% probability of success and a 25% discount rate results in ....
not to get it due to early stage and MOA (which is novel but unproven).
Get a detailed overview on how to lower bad cholesterol (LDL) and increase ...
Statins and other drugs can reduce LDL production by as much as 70 ... has
shown that his multipronged approach (diet, exercise, stress reduction, ...
Depending on your cholesterol levels, successfully reaching your target levels
will probably ...