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Role of Myocardial ATP-Sensitive Potassium Channels ... - Circulation


From the Department of Pharmacology, Bristol-Myers Squibb. Pharmaceutical ... Grover et al KATP and Al-Receptors in Preconditioning. 1311 artery for ... min glyburide (Sigma Chemical Co., St. Louis, Mo.) .... V * 51.94 3.61x R . 0.30 a cc u. N.

PLOS ONE: Impairment of Type I but Not Type III IFN Signaling by ...


Mar 31, 2015 ... All authors of this manuscript are employees of Bristol-Myers Squibb. ..... TaqMan minor groove binding (MGB) probe (Applied Biosystems); ... Transcriptional levels of type I and type III co-receptors, IFNAR2 and ..... Sarasin-Filipowicz M, Oakeley EJ, Duong FH, Christen V, Terracciano L, Filipowicz W, et al.

Full Text


Apr 1, 1997 ... BMS-180448, a member of this chemical class (Atwal et al., 1993, 1995), has ... reduced propensity to reduce action potential duration (Grover et al., 1995a), .... Radiolabeled 15 ± 3 μm diameter microspheres, <sup>57</sup>Co,<sup>113</sup>Sn, <sup>85</sup>Sr or ..... Ph.D., Department of Pharmacology, F1.4112, Bristol-Myers Squibb PRI, ...

Patent US20120301490 - Immunoconjugates, compositions for ...


Nov 29, 2012 ... Original Assignee, Bristol-Myers Squibb Company ... An immunoconjugate in which a phosphate-prodrugged DNA minor groove binding agent of formula (I), where X is .... 2002, 2006a, 2006b, 2009a, 2009b, and 2010; and Sufi et al. .... Each heavy chain comprises a heavy chain variable region (VH) and a ...

Identification of N-hydroxamic acid and N-hydroxy - Antiviral ...


influenza B virus (Betts, 1991, 1992; Hayden et al., 1991;. Hayden and Couch ... screen the Bristol-Myers Squibb chemical collection for ... subtype B virus, detergent solubilized (0.25%[v/v] Triton- ..... domain along with a separate RNA binding 'groove'. These .... 500 flM of ApG (Sigma Chemical Co., St Louis, MO), which.

Crystal Structure of a Heterodimeric Complex of RAR and RXR ...


This groove is known to contribute within the LBDs of PPARγ (Nolte et al. ..... antagonist BMS614 were generously provided by Bristol-Myers-Squibb, and .... We greatly acknowledge the excellent technical assistance of V. Andry, .... Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ.

See bibliography - Millennium Health


Princeton, NJ: Bristol-Myers Squibb Company; 2011. 9. .... Crews KR, Gaedigk A, Dunnenberger HM, et al. Clinical Pharmacogenetics Implementation. Consortium ... V, van Schaik RH. ..... Grover S, Kukreti R. HLA alleles and hypersensitivity.

Antibody–drug conjugates: current status and future directions

patofyziologie.lf1.cuni.cz/file/554/antibody-drug conjugates.pdf

Perez, et al., Antibody–drug conjugates: current status and future directions, Drug ... 1 Bristol-Myers Squibb Research & Development, Princeton, NJ 08543, USA ..... 5T4 and alpha v beta6 ..... covalently bind the minor groove of DNA, resulting in a lethal .... Bertozzi and co-workers utilized formylglycine-generating enzyme.

Judge Gregory M. Sleet - PlainSite


... et al v. Federal Housing Finance Agency et al .... 9/5/2014 · 1:14-cv-01131 · Bristol-Myers Squibb Co. et al v. ... v. Nang Kuang Pharmaceutical Co LTD et al ...

The mitochondrial KATP channel opener BMS-191095 reduces ...


May 31, 2006 ... Keita Mayanagi, Tamás Gáspár, Prasad V G Katakam, Béla Kis and David W Busija ... In addition, the effects of BMS-191095 on plasma and mitochondrial ... induced in mitochondria by BMS-191095 was less than by diazoxide (Kis et al, 2003, ... BMS-191095 (Bristol-Myers Squibb, Princeton, NJ, USA) was ...

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Bristol-Myers Escapes $3.4B Apotex Suit Over Plavix Deal - Law360


Mar 14, 2013 ... Bristol-Myers Squibb Co. and partner Sanofi-Aventis SA won a defense verdict Wednesday in a $3.4 billion ... The case is Apotex Inc. et al. v.



BRISTOL-MYERS SQUIBB COMPANY v. APOTEX, INC. et al, No. 3: 2010cv05810 - Document 142 (D.N.J. 2013) case opinion from the District of New Jersey ...

Bristol-Myers Seeks To Bust Genentech Cancer Drug ... - Mayer Brown


May 7, 2013 ... In a complaint, Bristol-Myers Squibb targeted Genentech Inc. and nonprofit cancer ... Hope are co-assignees of the patents, according to the suit. ... The case is Bristol-Myers Squibb Co. v. Genentech Inc. et al., case No.

Structural and functional characterization of CFE88: Evidence that a ...


To help address this issue, Bristol-Myers Squibb has developed a ... has been developed by Bristol-Myers Squibb to identify novel antifungal agents (Wang et al . .... For the former samples, 3D H(C)(CC)(CO)NH, 3D HCCH-TOCSY, and 4D .... model, these residues are expected to be in or near the SAH binding groove (Fig.

False Claims Cases Filed January 1, 2007 – June 30, 2013 - Navigant


Jun 28, 2013 ... Crawley V. Harrisburg Area Community College Et Al. Todd A. Crawley. Frank P. ...... Robert A. Grover, DO; Robert. A. Grover, DO, PA .... United States Of America Et Al V. Bristol Myers Squibb Company Et Al. United States of ...