Antineoplastic resistance, often used interchangeably with chemotherapy
resistance, is the ... Cancer cells can become resistant to multiple drugs by
various mechanisms, including: Altered membrane ...
Mechanisms underlying acquired resistance to pathway-targeted drugs are being
pursued ... breast and ovarian cancers with PARP inhibitors, and in basal cell ...
Since cancer cell selection obeys the ... acquired resistance phenotype and in
turn, alter their ...
Drug resistance is a major obstacle in drug efficacy that causes cancer cells to be
... or HER3 in lapatinib-resistant SKBR3 and BT474 breast cancer cell lines.
In contrast, acquired resistance develops in tumors that were initially sensitive to
... cancer expresses a different array of drug-resistance genes, and even cells
within ... In order to identify changes in gene expression in breast cancer cells
It is likely that early diagnosis of cancer drug resistance may eventually be ....
This study revealed that breast cancer cells could acquire the ability to express IL
Feb 2, 2015 ... After seeing that pan-ERBB inhibitors remain effective against ERBB2-positive
breast cancer cells with acquired resistance to anti-ERBB2 ...
Jan 6, 2016 ... Triple-negative breast cancer – named for the absence of three key receptors on
its cells – accounts ... Nor had the cells acquired the ability to pump the drugs out
of their interior (a common tactic of drug-resistant cancer cells).
Acquired resistance can occur very quickly after treatment begins in some
patients. ... cells may develop resistance to MPS1 inhibitors, a new type of cancer
ww5.komen.org/uploadedFiles/_Komen/Content/What_We_Do/We_Fund_Research/Research_Accomplishments/Susan G. Komen Science Buzz Fighting Drug Resistance in HER2 Breast Cancer.pdf
O Science Buzz! º. SUSCIſ) G. Fighting Drug Resistance in Her-2 Breast Cancer
... the tumor, allowing them to kill tumor cells while doing little harm to normal
cells. ... phenomenon, called “acquired drug resistance,” is a common problem.