Antineoplastic resistance, often used interchangeably with chemotherapy
resistance, is the ... Cancer cells can become resistant to multiple drugs by
various mechanisms, .... In breast cancer, drug ...
Mechanisms underlying acquired resistance to pathway-targeted drugs are being
... of treatment of BRCA-mutant breast and ovarian cancers with PARP inhibitors,
and in basal cell carcinoma patients defined by mutational activation of the Hh ...
Drug resistance is a major obstacle in drug efficacy that causes cancer cells to be
... or HER3 in lapatinib-resistant SKBR3 and BT474 breast cancer cell lines.
Sep 3, 2010 ... Cancer Cells Acquire Mitotic Drug Resistance Properties Through Beta ...... of
beta-tubulin isotypes in breast cancer cells resistant to docetaxel.
This review is focused on tumor drug resistance-related properties of CSCs and
... view, cancer cells that survived during chemotherapy and acquired drug ...
including P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and the
This allows tumor cells to avoid the toxic effects of the drug or molecular
processes ... Isis, for example, is using its antisense technology to develop drugs
to block the ... Annamycin is under development for the treatment of drug-
resistant breast ...
Evaluating HER2 amplification status and acquired drug resistance in breast
cancer cells using Raman spectroscopy. Bi X(1), Rexer B(2), Arteaga CL(2), Guo
Sep 5, 2014 ... However, cancer cells can also develop resistance to such .... response to
trastuzumab in HER2-positive breast cancer cells, and suggest that ...
Sep 25, 2014 ... Poised epigenetic states and acquired drug resistance in cancer ..... Poised
chromatin at the ZEB1 promoter enables breast cancer cell ...
Feb 3, 2015 ... However, primary or acquired drug resistance is the primary cause of the ...
Therefore, ER re-expression in ER-negative breast cancer cells for ...