Antineoplastic resistance, often used interchangeably with chemotherapy
resistance, is the ... Cancer cells can become resistant to multiple drugs by
various mechanisms, .... In breast cancer, drug ...
Mechanisms underlying acquired resistance to pathway-targeted drugs are being
pursued ... breast and ovarian cancers with PARP inhibitors, and in basal cell ...
Sep 5, 2014 ... However, cancer cells can also develop resistance to such ... in 30% of breast
cancer patients , and drug resistance can result after long ...
Sep 3, 2010 ... (2010) Cancer Cells Acquire Mitotic Drug Resistance Properties ...... of beta-
tubulin isotypes in breast cancer cells resistant to docetaxel.
Feb 2, 2015 ... After seeing that pan-ERBB inhibitors remain effective against ERBB2-positive
breast cancer cells with acquired resistance to anti-ERBB2 ...
In contrast, acquired resistance develops in tumors that were initially sensitive to
... cancer expresses a different array of drug-resistance genes, and even cells
within ... In order to identify changes in gene expression in breast cancer cells
To further illustrate this drug-specific effect, possible mechanisms that enable
breast cancer cells MCF-7 to acquire MDR to either paclitaxel (PTX) or
General mechanisms leading to cellular drug resistance ... the process of
selection drives the cells, in a rather extreme fashion, to develop mechanisms to
... non-Hodgkin's lymphomas, colon carcinoma, breast carcinoma and renal cell
They may develop multiple mechanisms of drug resistance, including ..... This
study revealed that breast cancer cells could acquire the ability to express IL-6, ...
Apr 9, 2015 ... Using human cell lines of the HER2-positive breast cancer subtype, researchers
detailed ... How breast cancer cells acquire drug resistance.