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Antineoplastic resistance

en.wikipedia.org/wiki/Antineoplastic_resistance

Antineoplastic resistance, often used interchangeably with chemotherapy resistance, is the ... Cancer cells can become resistant to multiple drugs by various mechanisms, .... In breast cancer, drug ...

Mechanisms of Acquired Resistance to Targeted Cancer Therapies

www.medscape.com/viewarticle/769431

Mechanisms underlying acquired resistance to pathway-targeted drugs are being pursued ... breast and ovarian cancers with PARP inhibitors, and in basal cell ...

Drug Resistance in Cancer: An Overview

www.ncbi.nlm.nih.gov/pmc/articles/PMC4190567/

Sep 5, 2014 ... However, cancer cells can also develop resistance to such ... in 30% of breast cancer patients [14], and drug resistance can result after long ...

Cancer Cells Acquire Mitotic Drug Resistance Properties Through ...

journals.plos.org/plosone/article?id=10.1371/journal.pone.0012564

Sep 3, 2010 ... (2010) Cancer Cells Acquire Mitotic Drug Resistance Properties ...... of beta- tubulin isotypes in breast cancer cells resistant to docetaxel.

New mechanism of acquired resistance to breast cancer drugs ...

www.sciencedaily.com/releases/2015/02/150202123301.htm

Feb 2, 2015 ... After seeing that pan-ERBB inhibitors remain effective against ERBB2-positive breast cancer cells with acquired resistance to anti-ERBB2 ...

Gene expression alterations in doxorubicin resistant MCF7 breast ...

www.sciencedirect.com/science/article/pii/S0888754312002297

In contrast, acquired resistance develops in tumors that were initially sensitive to ... cancer expresses a different array of drug-resistance genes, and even cells within ... In order to identify changes in gene expression in breast cancer cells that ...

Differential drug resistance acquisition to doxorubicin and paclitaxel ...

cancerci.biomedcentral.com/articles/10.1186/s12935-014-0142-4

To further illustrate this drug-specific effect, possible mechanisms that enable breast cancer cells MCF-7 to acquire MDR to either paclitaxel (PTX) or doxorubicin ...

Drug Resistance - The Oncologist - AlphaMed Press

theoncologist.alphamedpress.org/content/1/1/82.full

General mechanisms leading to cellular drug resistance ... the process of selection drives the cells, in a rather extreme fashion, to develop mechanisms to ... non-Hodgkin's lymphomas, colon carcinoma, breast carcinoma and renal cell cancer.

Cytokines in cancer drug resistance: Cues to new therapeutic ...

www.sciencedirect.com/science/article/pii/S0304419X16300270

They may develop multiple mechanisms of drug resistance, including ..... This study revealed that breast cancer cells could acquire the ability to express IL-6, ...

New approach to treat drug-resistant HER2--positive breast cancer ...

www.sciencedaily.com/releases/2015/04/150409133220.htm

Apr 9, 2015 ... Using human cell lines of the HER2-positive breast cancer subtype, researchers detailed ... How breast cancer cells acquire drug resistance.

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Mechanisms and insights into drug resistance in cancer - NCBI

www.ncbi.nlm.nih.gov

Mar 14, 2013 ... Cancer drug resistance continues to be a major impediment in .... and mitoxantrone resistance protein [MXR; also known as breast cancer ... Many cancer cells develop an overreliance or dependency on an oncogene. This is ...

Cancer multidrug resistance : Article : Nature Biotechnology

www.nature.com

This allows tumor cells to avoid the toxic effects of the drug or molecular processes ... Isis, for example, is using its antisense technology to develop drugs to block the ... Annamycin is under development for the treatment of drug- resistant breast ...

Prediction of signaling cross-talks contributing to acquired drug ...

bmcsystbiol.biomedcentral.com

Drug resistance is a major obstacle in drug efficacy that causes cancer cells to be ... or HER3 in lapatinib-resistant SKBR3 and BT474 breast cancer cell lines.