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Antineoplastic resistance

en.wikipedia.org/wiki/Antineoplastic_resistance

Antineoplastic resistance, often used interchangeably with chemotherapy resistance, is the ... Cancer cells can become resistant to multiple drugs by various mechanisms, .... In breast cancer, drug ...

Mechanisms of Acquired Resistance to Targeted Cancer Therapies

www.medscape.com/viewarticle/769431

Mechanisms underlying acquired resistance to pathway-targeted drugs are being ... of treatment of BRCA-mutant breast and ovarian cancers with PARP inhibitors, and in basal cell carcinoma patients defined by mutational activation of the Hh ...

Prediction of signaling cross-talks contributing to acquired drug ...

bmcsystbiol.biomedcentral.com/articles/10.1186/s12918-014-0135-x

Drug resistance is a major obstacle in drug efficacy that causes cancer cells to be ... or HER3 in lapatinib-resistant SKBR3 and BT474 breast cancer cell lines.

Cancer Cells Acquire Mitotic Drug Resistance Properties Through ...

journals.plos.org/plosone/article?id=10.1371/journal.pone.0012564

Sep 3, 2010 ... Cancer Cells Acquire Mitotic Drug Resistance Properties Through Beta ...... of beta-tubulin isotypes in breast cancer cells resistant to docetaxel.

Cancer stem cells and drug resistance: the potential of nanomedicine

www.ncbi.nlm.nih.gov/pmc/articles/PMC3376090/

This review is focused on tumor drug resistance-related properties of CSCs and ... view, cancer cells that survived during chemotherapy and acquired drug ... including P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and the  ...

Cancer multidrug resistance : Article : Nature Biotechnology

www.nature.com/nbt/journal/v18/n10s/full/nbt1000_IT18.html

This allows tumor cells to avoid the toxic effects of the drug or molecular processes ... Isis, for example, is using its antisense technology to develop drugs to block the ... Annamycin is under development for the treatment of drug- resistant breast ...

Evaluating HER2 amplification status and acquired drug resistance ...

www.ncbi.nlm.nih.gov/pubmed/24496495

Evaluating HER2 amplification status and acquired drug resistance in breast cancer cells using Raman spectroscopy. Bi X(1), Rexer B(2), Arteaga CL(2), Guo  ...

Drug Resistance in Cancer: An Overview - MDPI.com

www.mdpi.com/2072-6694/6/3/1769/pdf

Sep 5, 2014 ... However, cancer cells can also develop resistance to such .... response to trastuzumab in HER2-positive breast cancer cells, and suggest that ...

Poised epigenetic states and acquired drug resistance in cancer ...

www.nature.com/nrc/journal/v14/n11/abs/nrc3819.html

Sep 25, 2014 ... Poised epigenetic states and acquired drug resistance in cancer ..... Poised chromatin at the ZEB1 promoter enables breast cancer cell ...

Mechanisms of Gefitinib-mediated reversal of tamoxifen resistance ...

www.nature.com/articles/srep07835

Feb 3, 2015 ... However, primary or acquired drug resistance is the primary cause of the ... Therefore, ER re-expression in ER-negative breast cancer cells for ...

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New mechanism of acquired resistance to breast cancer drugs ...

www.sciencedaily.com

Feb 2, 2015 ... After seeing that pan-ERBB inhibitors remain effective against ERBB2-positive breast cancer cells with acquired resistance to anti-ERBB2 ...

Gene expression alterations in doxorubicin resistant MCF7 breast ...

www.sciencedirect.com

In contrast, acquired resistance develops in tumors that were initially sensitive to ... cancer expresses a different array of drug-resistance genes, and even cells within ... In order to identify changes in gene expression in breast cancer cells that ...

Prediction of signaling cross-talks contributing to acquired drug ...

www.ncbi.nlm.nih.gov

Jan 20, 2015 ... Prediction of signaling cross-talks contributing to acquired drug resistance in breast cancer cells by Bayesian statistical modeling. Azad AK(1) ...