Antineoplastic resistance, often used interchangeably with chemotherapy
resistance, is the ... Cancer cells can become resistant to multiple drugs by
various mechanisms, including: Altered membrane ...
Mechanisms underlying acquired resistance to pathway-targeted drugs are being
pursued ... breast and ovarian cancers with PARP inhibitors, and in basal cell ...
Sep 5, 2014 ... Overall, drug inactivation is a mechanism of cancer drug resistance ..... Taken
together, the drug resistance of cancer progenitor cells and the acquired drug ...
Human breast cancer cells can also exhibit drug resistance via ...
Since cancer cell selection obeys the ... acquired resistance phenotype and in
turn, alter their ...
This allows tumor cells to avoid the toxic effects of the drug or molecular
processes within the .... disease, and who had intrinsic or acquired resistance to
doxorubicin. ... Annamycin is under development for the treatment of drug-
resistant breast ...
Sep 3, 2010 ... (2010) Cancer Cells Acquire Mitotic Drug Resistance Properties ..... of beta-
tubulin isotypes in breast cancer cells resistant to docetaxel. FASEB ...
Feb 2, 2015 ... After seeing that pan-ERBB inhibitors remain effective against ERBB2-positive
breast cancer cells with acquired resistance to anti-ERBB2 ...
Jan 22, 2014 ... Breast cancer Taxane Doxorubicin Chemoresistance MCF-7 cell ABC ..... the
acquired drug resistance in MCF-7TXT/MCF-7DOX cells and the ...
Selection for cancer cells that are resistant to a particular drug: While it is thought
that ... These changes mean that dividing cancer cells acquire genetic changes
.... determined during the initial phase of breast and ovarian cancer diagnosis.3.
Dec 21, 2014 ... To further illustrate this drug-specific effect, possible mechanisms that enable
breast cancer cells MCF-7 to acquire MDR to either paclitaxel ...